Colleagues in Liver Disease Research, and in Life

Posted: 3/25/2016
When you ask Brett Spear about what he most admires in his wife and colleague, Martha Peterson, a smile instantly appears on his face. The pair, both professors in the University of Kentucky College of Medicine Department ofMicrobiology, Immunology and Molecular Genetics, has been married for 32 years and has two sons. Yet, because they have different last names, not everyone on campus recognizes their connection.  “When I meet people on campus, and they talk about how, ‘oh I just love Dr. Peterson,’ or ‘Martha's great, I was on a committee with her,’ and they'll say this and they don’t know I'm her husband,” Spear said. “So it's really fun... FULL STORY
Tags: Microbiology, Immunology, Faculty

MIMG Students Present Research Papers at International Meeting

Posted: 10/15/2015
Christina Savage and Will Arnold, MIMG doctoral students, have been invited to present results of their research in Vienna, Austria, at the International Conference on Lyme Borreliosis. Ms. Savage will give a talk on her studies on how the Borrelia burgdorferi SpoVG protein controls bacterial replication, and Mr. Arnold will present a poster describing his work on gene regulation by the bacterial master regulator, BpuR. Both are students in the laboratory of Professor Brian Stevenson, who will also present an invited talk on the laboratory¹s research. The ICLB is the world¹s largest conference on Lyme disease and other tick borne infections, and will be held in... FULL STORY

UK Researchers Find “Dormant” Parasite Cysts Are Actually Quite Active

Posted: 9/8/2015
A new University of Kentucky study in the journal mBio shows that tissue cysts of the parasite Toxoplasma gondii, long thought to be dormant, are quite active. Led by Anthony Sinai, professor at the UK College of Medicine, the study has significant implications on the understanding of chronic toxoplasmosis in the brain, a condition suggested to contribute to a range of neurological diseases including schizophrenia in humans, and the modulation of behavior in rodents. Toxoplasmosis can be acquired from the droppings of infected cats as well as the consumption of tissue cyst contaminated meat,infects roughly one-third of the human population. Infected individuals... FULL STORY
Tags: research

Clay County School Visit

Posted: 6/25/2015
On March 30 and 31st the University of Kentucky hosted a total of 150 students from Oneida and Manchester elementary schools in Clay County Kentucky. These students are participants in a study called The Clay County Clock Study funded by CCTS. The co-PIs of the study, Jody Clasey from Kinesiology and Karyn Esser from Physiology, arranged for the students to get a “hands on” look at science at UK. The students did 4 rotations around campus including Engineering, Cardiology, Human Performance, and Microbiology. Dr. Beth Garvy, with help from Dr. Carol Pickett, Melissa Hollifield, Heather Evans, Sarai Kidd, and Dr. Brian Stevenson, provided a microbiology experience for the... FULL STORY

Animesh Dhara Ph.D. & Elizabeth Watts B.S. win best posters

Posted: 6/25/2015
Congratulations to Animesh Dhara Ph.D.(postdoc) and Elizabeth Watts B.S. (lab manager) from the Sinai Lab for each having been recognized as presenting the best posters at the 13th International Congress on Toxoplasmosis and T. gondii Biology held in Gettysburg PA.  Animesh and Elizabeth’s posters were selected on the basis of both the quality of the work, its display and presentation.  The top 12 posters out of a total of 221 poster presentations were chosen by the attendees at the conference for this honor. Dr. Animesh Dhara whose poster was titled, “A Toxoplasma deubiquitinase TgOTU1 regulates the fidelity of endodyogeny: a potential link between... FULL STORY

UK Researcher Earns NIH Funding to Expand Gender-Based Studies on

Posted: 9/30/2014
In her research, Sarah D'Orazio, associate professor in the University of Kentucky Department of Microbiology, Immunology and Molecular Genetics, investigates why some people get sicker than others after ingesting the foodborne bacterial pathogen Listeria monocytogenes. Using a mouse model, her research team observed that a subset of mice most susceptible to the dangerous bacteria share one common trait: they are all female. With supplemental funding from the National Institutes of Health (NIH), D'Orazio has the resources to explore why Listeria infection affects females more severely than their male counterparts. Part of an effort to promote sex-based research,... FULL STORY
Tags: NIH Award, Microbiology

One Year After NCI Designation, Markey Continues to Grow

Posted: 7/11/2014
A year ago, a crowd of hundreds gathered in Pavilion A of the University of Kentucky Chandler Hospital to celebrate a long-awaited special announcement – the unveiling of the UK Markey Cancer Center as the state's first and only National Cancer Institute-designated cancer center. The designation was the culmination of years of tireless work by the faculty and staff of Markey and its supporting service lines and colleges – all guided by Director Dr. Mark Evers, who came to UK in 2009 with the vision of propelling Markey to NCI designation. "Even before earning the NCI designation, we'd already taken extraordinary steps in the past few years in terms of combating... FULL STORY
Tags: Markey Cancer Center

Silent Auction Benefits Shoulder to Shoulder Clinic in Ecuador

Posted: 4/2/2014
The University of Kentucky Chapter of the International Federation of Medical Student Associations (IFMSA) will host the 10th annual Art of Healing silent auction on Wednesday, April 2. The auction will be held in Biological and Biomedical Sciences Research Building (BBSRB) atrium from noon to 5 p.m. Winning bidders may pick up their art from 5 p.m. to 6 p.m. The auction items feature the handiwork of local and international artists and current students, including pottery, paintings, wood carvings, and accessories. Proceeds from the art auction benefit the Shoulder to Shoulder clinic in Ecuador. Shoulder to Shoulder, an initiative supported by many of the... FULL STORY
Tags: Medical Education, Auction

Bastos-Carvalho Receives Bayer Grant

Posted: 1/13/2014
Ana Bastos-Carvalho, a visiting scholar in the Ambati research group in the Department of Ophthalmology and Visual Sciences at the University of Kentucky College of Medicine, received the Global Ophthalmology Research Award from Bayer HealthCare for her research, "Mechanisms of geographic atrophy expansion in age-related macular degeneration." http://www.bayer-ophthalmology-awards.com/html/b-about-c.html “We are studying age-related macular degeneration (AMD), the disease responsible for most cases of legal blindness in the American elderly population”, Bastos-Carvalho said. “The project awarded by Bayer focuses on unraveling how AMD progresses, which will hopefully... FULL STORY
Tags: Ophthalmology and Visual Sciences, 490

Creating a Culture of Collaboration for Research at UK and Beyond

Posted: 1/10/2014
There's a proverb in the business world that says, "If you don’t know, hire someone who does." In the world of translational research, the saying might go like something this: "If you don't have the expertise or resources, collaborate with someone who does." The nature of translational science -- the process of turning a basic science discovery into applications for human patients -- is inherently multidimensional. Moving from the "bench to bedside" is a process that runs the gamut of biomedical research, incorporating laboratory and animal studies, clinical trials, drug and device development, regulatory issues, grant writing and more. Each step requires... FULL STORY
Tags: CCTS, 490, Center for Clinical and Translational Science

UK's Arts In Healthcare Program Announces Holiday Programming

Posted: 12/2/2013
Everyone wants to be home for the holidays. Unfortunately, hospital patients don't have that luxury. For those who are unable to enjoy the comforts of a holiday at home, the UK Arts in Healthcare program has scheduled a series of events to help bring the holidays to the hospital. Carolers, pianists, harpists and more will bring holiday cheer to patients, visitors and staff in December. Of particular note: UK HealthCare's own Dr. Jay Zwischenberger will be performing at 1 p.m., Dec. 12, in the Pavilion A of UK Chandler Hospital. Carolers from Deep Springs Elementary School will be performing at noon, Dec.13, Pavilion A of UK Chandler Hospital. Carolers from the... FULL STORY
Tags: Arts in Healthcare